Title:

Investigation of a Polymer Structure Suitable for Bioconjugation to Create an Anti-icing Coating

Polymers as a whole are incredibly versatile in that they may be designed to host a number of functional groups that may each serve their own purpose. The structure of these macromolecules may be modified to a great degree in order to suit the necessary application. This paper investigates both the ideal structure and synthesis techniques to design a polymer that is capable of bioconjugation with amino acid residues and ultimately proteins. RAFT polymerization is used to create a copolymer, in which one monomer contains a pyridyl disulfide functional group that is needed for the necessary bioconjugation. Ideally, this copolymer will be able to conjugate with an antifreeze protein (AFP) via a disulfide exchange reaction. Ultimately, this unique polymer will be display properties of ice recrystallization inhibition (IRI).

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